Systematic review on the instruments used for measuring the association of the level of multimorbidity and clinically important outcomes
Autor: | Bridget L. Ryan, Eng Sing Lee, Fang Yan Wong, Sok Huang Teo, Elaine Qiao-Ying Ho, Hui Li Koh, Moira Stewart, Martin Fortin |
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Přispěvatelé: | Lee Kong Chian School of Medicine (LKCMedicine) |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Adult
medicine.medical_specialty protocols & guidelines Population MEDLINE CINAHL Comorbidity 03 medical and health sciences primary care 0302 clinical medicine Quality of life (healthcare) Medicine and Health Sciences Medicine Humans Medical physics Medicine [Science] 030212 general & internal medicine education education.field_of_study general medicine (see Internal Medicine) Primary Health Care business.industry 030503 health policy & services Medical record Multimorbidity General Medicine medicine.disease Systematic review protocols and guidelines Scale (social sciences) Quality of Life 0305 other medical science business General practice / Family practice Delivery of Health Care |
Zdroj: | BMJ Open, Vol 11, Iss 5 (2021) Family Medicine Publications BMJ Open |
ISSN: | 2044-6055 |
Popis: | ObjectivesThere are multiple instruments for measuring multimorbidity. The main objective of this systematic review was to provide a list of instruments that are suitable for use in studies aiming to measure the association of a specific outcome with different levels of multimorbidity as the main independent variable in community-dwelling individuals. The secondary objective was to provide details of the requirements, strengths and limitations of these instruments, and the chosen outcomes.MethodsWe conducted the review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PROSPERO registration number: CRD42018105297). We searched MEDLINE, Embase and CINAHL electronic databases published in English and manually searched the Journal of Comorbidity between 1 January 2010 and 23 October 2020 inclusive. Studies also had to select adult patients from primary care or general population and had at least one specified outcome variable. Two authors screened the titles, abstracts and full texts independently. Disagreements were resolved with a third author. The modified Newcastle-Ottawa Scale was used for quality assessment.ResultsNinety-six studies were identified, with 69 of them rated to have a low risk of bias. In total, 33 unique instruments were described. Disease Count and weighted indices like Charlson Comorbidity Index were commonly used. Other approaches included pharmaceutical-based instruments. Disease Count was the common instrument used for measuring all three essential core outcomes of multimorbidity research: mortality, mental health and quality of life. There was a rise in the development of novel weighted indices by using prognostic models. The data obtained for measuring multimorbidity were from sources including medical records, patient self-reports and large administrative databases.ConclusionsWe listed the details of 33 instruments for measuring the level of multimorbidity as a resource for investigators interested in the measurement of multimorbidity for its association with or prediction of a specific outcome. |
Databáze: | OpenAIRE |
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