Transforming growth factor beta 1 as a prognostic factor in pulmonary adenocarcinoma
| Autor: | Susumu Kodaira, Yasuki Yamamoto, T Hashizume, K. Kikuchi, Iwao Takanami, T Imamura |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Cytoplasm Prognostic factor medicine.medical_specialty Pathology Lung Neoplasms Pulmonary adenocarcinoma Adenocarcinoma Gastroenterology Pathology and Forensic Medicine Transforming Growth Factor beta Internal medicine medicine Humans Paraffin embedding Aged Aged 80 and over Paraffin Embedding biology business.industry Respiratory disease Five-year survival rate General Medicine Transforming growth factor beta Middle Aged Prognosis medicine.disease Immunohistochemistry Multivariate Analysis biology.protein Female business Research Article |
| Zdroj: | Journal of Clinical Pathology. 47:1098-1100 |
| ISSN: | 0021-9746 |
| Popis: | AIMS--To evaluate the efficacy of transforming growth factor beta (TGF-beta) for the prognosis of pulmonary adenocarcinoma. METHODS--TGF-beta was detected immunohistochemically using the avidin-biotin-peroxidase complex technique in resected pulmonary adenocarcinomas from 88 patients. RESULTS--Of the 88 patients, 39 were TGF-beta negative and 45 TGF-beta positive. The five year survival rate was 56% for the TGF-beta negative and 16% for the TGF-beta positive group. CONCLUSIONS--TGF-beta can be used as a prognostic factor in pulmonary adenocarcinoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|