Hepatitis B Surface Antigen in Blood Donors: Further Observations
| Autor: | Robert L. Hirsch, Wolf Szmuness, E. J. Harley, H. Ikram, Alfred M. Prince, R. W. Levine |
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| Rok vydání: | 1975 |
| Předmět: |
Adult
Male HBsAg Black People Blood Donors Hepatitis b surface antigen White People ABO Blood-Group System Hepatitis B Antigens Epitopes Asian People Antigen medicine Humans Immunology and Allergy Antigen testing Antigens Viral Volunteer Hepatitis Rh-Hr Blood-Group System business.industry Cell Membrane Middle Aged Hepatitis B medicine.disease Virology Infectious Diseases Jews Immunology Educational Status Female business Follow-Up Studies |
| Zdroj: | Journal of Infectious Diseases. 131:111-118 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/131.2.111 |
| Popis: | A survey of 128,000 volunteer blood donors from the Greater New York metropolitan area revealed that first-time male donors were positive for hepatitis B surface antigen (HBsAg) 2.5 times more frequently than were first-time female donors; Negroes and Mongols were positive four to 20 times more frequently than Caucasians. The ratio of ad to ay seemed to be higher in non-Caucasian antigen carriers than in Caucasian carriers. Among both Caucasians and non-Caucasians the rate of positivity declined after the age of 50. An excess prevalence of HBsAg was observed in donors with the lowest level of education and in those with the highest level. HBsAg was detectable nine times less frequently among repeat donors than among first-time donors (0.2 vs.1.90 per 1,000). Detection of HBsAg was unrelated to ABO-Rh blood groups. Several mechanisms for these wide variations of antigen detection are possible. |
| Databáze: | OpenAIRE |
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