Challenges of left atrial appendage closure device and anticoagulation in a patient with immune thrombocytopenia (ITP)
| Autor: | Neelambuj Regmi, Eskara Pervez, Tanveer Mir, Mohammed Uddin, Muhammad Usama, Anupama Kottam |
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| Rok vydání: | 2023 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Platelet disorder Case Report Thromboembolic stroke 030105 genetics & heredity 03 medical and health sciences 0302 clinical medicine Internal medicine Atrial Fibrillation Medicine Humans Atrial Appendage Thrombus Purpura Thrombocytopenic Idiopathic Interventional cardiology business.industry Anticoagulants Atrial fibrillation General Medicine Guideline medicine.disease Thrombosis Immune thrombocytopenia Stroke Treatment Outcome Cardiology business 030217 neurology & neurosurgery |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| Popis: | Among patients with atrial fibrillation (AF) who have high risk of bleeding secondary to haematologic disorders, left atrial appendage (LAA) occlusion therapy has been shown to be an excellent alternative to long-term use of oral anticoagulation for thromboembolic stroke prevention. However, there remains a major concern of device-associated thrombosis post-procedure, that can lead to life-threatening embolic events. To this date, there is no systematic guideline for the selection and management of patients with haematological disorders with LAA occlusion therapy, especially in those with platelet disorders such as immune thrombocytopenia (ITP). Patients with platelet disorders are at a higher risk for bleeding; however, that does not prevent such patients from thromboembolic events secondary to AF. We present a case of ITP with permanent AF, where an LAA device was complicated by thrombus formation due to challenges faced with anticoagulation therapy. |
| Databáze: | OpenAIRE |
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