Intrapulmonary artery balloon counterpulsation (PABC) improves outcome in post-ischemic cardiogenic shock
| Autor: | S. Nour, N. Magkoutis, R. Ouardani, Chantal Kang, O. Bailliart, Michel Bonneau, G. Sideris, Sebastian Voicu |
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| Přispěvatelé: | Centre de Recherche en Imagerie Interventionnelle (CR2I), Institut National de la Recherche Agronomique (INRA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), European Society of Cardiology. |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Cardiac output
medicine.medical_specialty business.industry Cardiogenic shock [SDV]Life Sciences [q-bio] Ischemia Balloon medicine.disease medicine.anatomical_structure Shock (circulatory) Anesthesia Internal medicine medicine.artery Pulmonary artery medicine Cardiology Myocardial infarction medicine.symptom Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | European Heart Journal Congress of the European-Society-of-Cardiology (ESC) Congress of the European-Society-of-Cardiology (ESC), European Society of Cardiology., Aug 2013, Amsterdam, Netherlands. ⟨10.1093/eurheartj/eht307.P447⟩ |
| DOI: | 10.1093/eurheartj/eht307.P447⟩ |
| Popis: | Purpose: To examine whether in a model of cardiogenic shock complicating left anterior descending (LAD) artery occlusion, changes in ventricular hemodynamics due to an intrapulmonary artery balloon counterpulsation (PABC) may be associated with improved short-term outcome at 150 minutes. Methods: Ten down size pigs weighing 35±5 kg of both sexes were sedated, intubated and mechanicallly ventilated. Myocardial infarction was induced by insertion of a vascular plug (Amplatzer®) into the proximal part of LAD. Medical treatment was chosen according to European Society of Cardiology (ESC) Guidelines of 2010. All animals had a counterpulsation balloon placed in the pulmonary artery trunk and the frequency of counterpulsation was set to 100/min, independent of the animal's heart rhythm. (In the test group (n=5), counterpulsation was started as soon as hemodynamic parameters worsened, i.e.: a) severe ventricular arrhythmia occurred, or b) mean blood pressure (MBP) dropped more than 30% compared to baseline, or c) cardiac output measured by Vigileo system decreased to less than 40% compared to baseline. The counterpulsation was maintained for 10 minutes. The control group (n=5) received no conterpulsation. Results: The test group had statistically significant improved short-term survival rates (100% vs 60%, p |
| Databáze: | OpenAIRE |
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