Detection of human parvovirus B19 in serum samples from children under 5 years of age with rash-fever illnesses in the Democratic Republic of the Congo
| Autor: | Elisabeth Simbu Pukuta, Steve Ahuka, Olivier Mbaya Tshiani, Michel Ntetani Aloni, Jean-Jacques Muyembe, Tony Bokalanga Wawina, Christopher J. Kasanga |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty Fever 030231 tropical medicine Human parvovirus Parvovirus B19 Antibodies Viral Rubella Measles Article lcsh:Infectious and parasitic diseases 03 medical and health sciences 0302 clinical medicine Internal medicine Genotype medicine Parvovirus B19 Human Humans lcsh:RC109-216 030212 general & internal medicine biology business.industry Infant General Medicine Exanthema medicine.disease Serum samples Rash 3. Good health Infectious Diseases Immunoglobulin M IgM antibody Child Preschool Immunology DNA Viral Etiology biology.protein Democratic Republic of the Congo Rash–fever illnesses Female medicine.symptom business Measles/rubella |
| Zdroj: | International Journal of Infectious Diseases International Journal of Infectious Diseases, Vol 65, Iss, Pp 4-7 (2017) |
| Popis: | BACKGROUND: It has been demonstrated that infection with human parvovirus B19 (B19V) is associated with rash-fever illnesses. The present study aimed to investigate B19V as an aetiological agent of rash-fever syndromes in Congolese children confirmed as measles and rubella IgM-negative. An ELISA IgM test and PCR were performed to screen for B19V. METHODS: A total of 177 archived serum samples were randomly selected from the measles biobank of the National Institute for Biomedical Research (INRB). Samples were investigated for anti-B19V IgM and B19V DNA. These samples originated from children |
| Databáze: | OpenAIRE |
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