Association Between Recent Cannabis Consumption and Withdrawal-Related Symptoms During Early Abstinence Among Females With Smoked Cocaine Use Disorder
| Autor: | Carla Hervê Moram Bicca, Thiago Wendt Viola, João Vítor Nóbrega e Mélo-Pereira, Breno Sanvicente-Vieira, João Paulo Ottolia Niederauer, Leonardo Melo Rothmann, Rodrigo Grassi-Oliveira, Joy M. Schmitz, Bruno Kluwe-Schiavon |
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| Přispěvatelé: | University of Zurich |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Longitudinal study Substance-Related Disorders media_common.quotation_subject 610 Medicine & health 01 natural sciences Article 03 medical and health sciences Severity assessment Cocaine-Related Disorders 2738 Psychiatry and Mental Health 0302 clinical medicine Cocaine Smoke Medicine Humans 2736 Pharmacology (medical) Pharmacology (medical) 030212 general & internal medicine Longitudinal Studies 0101 mathematics Psychiatry Association (psychology) Effects of cannabis media_common Cannabis biology business.industry 010102 general mathematics Abstinence biology.organism_classification Substance Withdrawal Syndrome Psychiatry and Mental health 10054 Clinic for Psychiatry Psychotherapy and Psychosomatics Cocaine use Female Substance use business |
| Zdroj: | J Addict Med |
| DOI: | 10.5167/uzh-222758 |
| Popis: | BACKGROUND: The effects of cannabis on clinical outcomes of treatment services for other drug use disorders remains unclear. The primary aim of the current study was to investigate the effects of recent cannabis consumption on the severity of cocaine withdrawal and depressive symptoms during a 3-week inpatient treatment program for women with cocaine use disorder. The second goal of this study was to test the effect of recent alcohol or tobacco use on the aforementioned outcomes. METHODS: This was a longitudinal study with 2 assessment time points: at enrollment and upon discharge from a medically managed intensive inpatient unit. The sample was composed of 214 early abstinence females with cocaine use disorder. Cocaine withdrawal and depressive symptoms were measured using the Cocaine Selective Severity Assessment (CSSA) and the Beck Depressive Inventory (BDI-II). Recent substance use was evaluated using the Addiction Severity Index (ASI-6). RESULTS: Patients with cocaine use disorder and with frequent recent cannabis use reported higher severity of cocaine withdrawal and depressive symptoms after 3 weeks of inpatient treatment. Neither recent alcohol nor tobacco use was associated with increased CSSA or BDI outcomes, suggesting these substances play a minor role compared to recent cannabis use in affecting withdrawal-related symptoms. CONCLUSIONS: The assessment of recent cannabis use may help identify patients in need of additional treatment to manage severe cocaine withdrawal symptoms and depressive symptoms during early abstinence. |
| Databáze: | OpenAIRE |
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