Sex Differences in 1-Year Outcomes After Percutaneous Coronary Intervention in the Veterans Health Administration
| Autor: | Melissa M. Farmer, Maggie A. Stanislawski, Lauren E Thompson, Stacie L. Daugherty, P. Michael Ho, Mary E. Plomondon, Bevanne Bean-Mayberry, Nataria T. Joseph, Jessica L. Zuchowski, Elizabeth M. Yano |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Time Factors medicine.medical_treatment Population Myocardial Infarction Veterans Health Comorbidity Coronary Artery Disease 030204 cardiovascular system & hematology Coronary artery disease 03 medical and health sciences Sex Factors 0302 clinical medicine Percutaneous Coronary Intervention Risk Factors Internal medicine medicine Humans Obesity cardiovascular diseases 030212 general & internal medicine Myocardial infarction education Adverse effect Retrospective Studies Veterans Cardiac catheterization Sex Characteristics education.field_of_study business.industry Percutaneous coronary intervention General Medicine Original Articles medicine.disease United States United States Department of Veterans Affairs Treatment Outcome Emergency medicine Conventional PCI Cardiology Female business Mace |
| Popis: | Advancements in percutaneous coronary intervention (PCI) for treating obstructive coronary artery disease have reduced major adverse events, including mortality. Yet, evidence as to whether women and men experience similar outcomes is mixed. The objective was to examine sex differences in 1-year major adverse cardiac outcomes for the national population of patients undergoing PCI at Veterans Health Administration (VA) cardiac catheterization laboratories.All Veterans undergoing PCI at VA hospitals between October 1, 2007 and September 30, 2013 (N = 64,757; Women = 1,040) were included. Cox proportional hazards models compared 1-year postprocedural outcomes [rehospitalization for myocardial infarction (MI), all-cause mortality, and major adverse cardiovascular events (MACE)] by sex.Women Veterans undergoing PCI were more likely to be younger, black, obese, and have chronic depression and less likely to have common cardiovascular risk factors and to have had prior cardiac events than Veteran men. One-year rates for women versus men were 2.1% and 2.5% for rehospitalization (p-value = 0.57); 3.5% and 4.9% for mortality (p-value = 0.14), and 5.4% and 6.9% for MACE (p-value = 0.18). There were no significant sex differences in any of the outcomes in Cox proportional hazards models.Despite differences in clinical risk factors at the time of PCI, women and men Veterans treated at VA cardiac catheterization laboratories experienced comparable 1-year rehospitalization for MI, mortality, and MACE post-PCI. These results demonstrated similar 1-year post-PCI outcomes for men and women in a national population of patients who have more comorbidities and mental health issues than the general population. |
| Databáze: | OpenAIRE |
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