A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae
| Autor: | Melinda Kovács, Roland Pósa, Tamás Donkó, Stoycho D. Stoev, Imre Repa, Tibor Magyar |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Lung Diseases
Pathology medicine.medical_specialty Swine 040301 veterinary sciences Health Toxicology and Mutagenesis Computed tomography Biology Toxicology Fumonisins 01 natural sciences 0403 veterinary science Gross examination chemistry.chemical_compound Mycoplasma hyopneumoniae medicine Animals Edema Lung Pathological Fumonisin B1 medicine.diagnostic_test 010401 analytical chemistry Public Health Environmental and Occupational Health 04 agricultural and veterinary sciences Pneumonia of Swine Mycoplasmal biology.organism_classification 0104 chemical sciences medicine.anatomical_structure chemistry Bronchointerstitial pneumonia Female Tomography X-Ray Computed Caudal lobe |
| Zdroj: | Toxicology and Industrial Health. 32:998-1012 |
| ISSN: | 1477-0393 0748-2337 |
| DOI: | 10.1177/0748233714543735 |
| Popis: | A more complicated pathology was observed in female pigs infected with Mycoplasma hyopneumoniae, when the same were exposed to 20 ppm dietary levels of fumonisin B1 (FB1) starting 14 days before infection for a period of 42 days as was assessed by gross pathology and pathomorphological examinations or computed tomography, and also manifested by the strong deterioration of the pneumonic process in two pigs and the subsequent euthanizing of one pig. Typical damages in FB1-fed pigs were a strong oedema in the lung and slight oedema in the other internal organs and mild degenerative changes in the kidneys, whereas the typical pathomorphological changes in M. hyopneumoniae-infected pigs corresponded to the morphologic pattern of a catarrhal bronchointerstitial pneumonia more pronounced in the cranial and middle lobes or in the cranial third of the caudal lobe of the lung. The pigs treated by both pathogens (toxic and infectious) revealed strong oedematous changes in the interstitium of lung in addition to deteriorated and extended bronchointerstitial pneumonic process. |
| Databáze: | OpenAIRE |
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