EFFECTS OF INDUCED HYPERTHERMIA IN MULTIPLE SCLEROSIS: DIFFERENCES IN VISUAL ACUITY DURING HEATING AND RECOVERY PHASES

Autor:	Floyd A. Davis, Joel Michael
Rok vydání:	2009
Předmět:	Hyperthermia Base line Multiple Sclerosis Visual acuity business.industry Multiple sclerosis Visual Acuity Optic Nerve Hyperthermia Induced General Medicine medicine.disease Body Temperature Text mining Neurology Anesthesia Humans Medicine Neurology (clinical) medicine.symptom business
Zdroj:	Acta Neurologica Scandinavica. 49:141-151
ISSN:	1600-0404 0001-6314
DOI:	10.1111/j.1600-0404.1973.tb01286.x
Popis:	Visual acuity in five multiple sclerosis (MS) patients was quantitatively monitored during the induction of hyperthermia and the subsequent spontaneous return of body temperature to base line (“cooling”). During heating acuity decreased monotonically. During “cooling” acuity was restored but, in three of the five patients, along a different temperature-acuity trajectory; that is, acuity at any temperature during “cooling” tended to be better than acuity at the same temperature reached during heating. In two patients acuity upon return to base-line temperature was significantly better than it had been before the induction of hyperthermia; in one case the difference was striking and significant at the .001 level. The difference in the second case was smaller but also significant (p < 0.02). The significance of these findings in helping to better understand the physiologic basis of temperature effects in MS is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff2b3451bd2cedd08adb07804ece54e https://doi.org/10.1111/j.1600-0404.1973.tb01286.x Zobrazit plný text záznamu