Usefulness of lymphoscintigraphy and intraoperative gamma probe detection in the identification of sentinel nodes in cervical cancer
| Autor: | Hyung Sun Sohn, Soo Kyo Chung, Sung Eun Namkoong, Sung Hoon Kim, Yong-An Chung, Chae Chun Rhim |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
medicine.medical_specialty Uterine Cervical Neoplasms Sulphur colloid Sensitivity and Specificity Monitoring Intraoperative Biopsy Humans Medicine Radiology Nuclear Medicine and imaging In patient Radical Hysterectomy Radionuclide Imaging Aged Cervical cancer medicine.diagnostic_test Sentinel Lymph Node Biopsy business.industry Reproducibility of Results General Medicine Middle Aged Sentinel node medicine.disease Surgery Dissection Lymphatic Metastasis Lymph Node Excision Female Lymph Nodes Radiology business Tomography Emission-Computed Gamma probe |
| Zdroj: | European Journal of Nuclear Medicine and Molecular Imaging. 30:1014-1017 |
| ISSN: | 1619-7089 1619-7070 |
| DOI: | 10.1007/s00259-003-1195-0 |
| Popis: | The aim of our study was to prospectively assess the clinical usefulness of sentinel lymphoscintigraphy and intraoperative gamma probe detection in identifying sentinel nodes (SNs) in patients with early cervical carcinoma. Between 6 and 24 h before radical hysterectomy, lymphoscintigrams were obtained following peritumoural injection of technetium-99m antimony sulphur colloid in 26 patients (mean age 45 years, range 32-71 years) with cervical cancer (FIGO I-IIa). Scanning for radioactive nodes was performed using a hand-held collimated gamma-detecting probe in the initial stages of the main operation, during and before exposure of the retroperitoneal spaces. After separation and removal of radioactive, blue nodes, specimens were submitted for pathological evaluation. SNs were successfully localised using a combination of lymphoscintigraphy and intraoperative gamma probe detection in all 26 cases. However, in two of the 26 cases, SNs were only localisable using the gamma-detecting probe. A histologically positive SN was found in only one case. It is concluded that, in cervical cancer, lymphoscintigraphy and SN biopsy using a gamma-detecting probe are easy and reliable methods for the detection of SNs and are of value in defining the necessity and extent of node dissection. |
| Databáze: | OpenAIRE |
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