Superior Outcomes With Continuing Tenofovir Versus Switching to Zidovudine in Second-Line Antiretroviral Therapy in Haiti

Autor: Samuel Pierre, Iryna Bocharova, Catherine Nguyen, Fabienne Homeus, Gaetane Julmiste, Youry Macius, Vanessa Rouzier, Patrice Severe, Marie Marcelle Deschamps, Colette Guiteau Moise, Clovy Bellot, Johnny Wu, Vanessa R Rivera, Rochelle Sun, Jean W Pape, Bernard Liautaud, Serena P Koenig
Rok vydání: 2021
Předmět:
Zdroj: Open Forum Infectious Diseases
ISSN: 2328-8957
DOI: 10.1093/ofid/ofab559
Popis: We compared viral suppression rates between patients who continued tenofovir disoproxil fumarate (TDF)/lamivudine (3TC) vs switched to zidovudine (ZDV)/3TC in combination with a boosted protease inhibitor after failure of first-line efavirenz/TDF/3TC. We found higher rates of viral suppression with continued TDF/3TC compared with switching to ZDV/3TC.
Databáze: OpenAIRE