Optimization of low-energy electron beam production for superficial cancer treatments by Monte Carlo code

Autor:	Navid Khaledi, Xufei Wang, Rana Akbarpoor, Farhad Samiei
Rok vydání:	2019
Předmět:	Electron beam Skin Neoplasms Materials science Monte Carlo method Electrons Context (language use) Electron lcsh:RC254-282 Imaging phantom Linear particle accelerator Optics Neoplasms Humans Radiology Nuclear Medicine and imaging Monte Carlo Monte Carlo N-Particle (MCNP) skin cancer business.industry Radiotherapy Planning Computer-Assisted Radiotherapy Dosage General Medicine lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens spoiler Oncology Cathode ray Slab Particle Accelerators business Monte Carlo Method Algorithms Beam (structure)
Zdroj:	Journal of Cancer Research and Therapeutics, Vol 15, Iss 3, Pp 475-479 (2019)
ISSN:	0973-1482
Popis:	Context: Low energy electron beam has been being used widely for superficial cancer treatments. In the current study a design for production of very low energy electron beam, by different thickness of Perspex spoilers, is presented that may be used for skin cancer. Aims: MCNPX Monte Carlo code was used for modeling and simulations in the current study. An energy spoiler Perspex was modeled for degrading 4 MeV electron beam of Varian 2300 CD Linac. Materials and Methods: The thicknesses of 3, 7, and 10 mm were applied before electron applicator at a distance of 42 cm from phantom surface. Dosimetric properties of new electron beams including Rp, Dmax, E0, as well as the penumbra of the beam were investigated. Results: For the 3 mm spoiler, the superficial beam output decreased to 77%, and the Dmax, R90, R50, and RP were shifted to the depths of 4, 6, 9, and 12 mm, respectively. While for 10 mm filter the results were 5.2, 3.0 and 5.0 mm for R90, R50, and Rp, respectively. In addition, the surface dose was 93% and the Dmax was shifted to the depth of 1mm for the 10mm Perspex spoiler slab. Conclusions: The presented beam provides a novel surface dose, Dmax, and RP which can be applicable for treatment of skin cancers with minimum dose to the beyond normal tissues.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe20456026f4b9fe12c28efdc387dc7 https://doi.org/10.4103/jcrt.jcrt_203_18 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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