Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris
| Autor: | Gabriel P. Krestin, Carlos Van Mieghem, Nico R. Mollet, Pim J. deFeyter, Giuseppe Runza, Francesca Pugliese, Willem B. Meijboom, Patrizia Malagutti, Timo Baks, Filippo Cademartiri |
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| Přispěvatelé: | Radiology & Nuclear Medicine, Cardiology |
| Rok vydání: | 2006 |
| Předmět: |
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medicine.medical_specialty Contrast Media Coronary Angiography Sensitivity and Specificity Angina Pectoris Predictive Value of Tests Positive predicative value Image Interpretation Computer-Assisted Medicine Humans Radiology Nuclear Medicine and imaging Bolus tracking Metoprolol Neuroradiology Aged Aged 80 and over medicine.diagnostic_test business.industry Ultrasound Coronary Stenosis Interventional radiology General Medicine Middle Aged Predictive value of tests Female Tomography Radiology business Tomography Spiral Computed medicine.drug |
| Zdroj: | European Radiology, 16(3), 575-582. Springer-Verlag |
| ISSN: | 0938-7994 |
| Popis: | Multislice computed tomography (CT) is an emerging technique for the non-invasive detection of coronary stenoses. While the diagnostic accuracy of 4-slice scanners was limited, 16-slice CT imagers showed promising results due to increased temporal and spatial resolution. These technical advances prompted us to evaluate the diagnostic performance of 64-slice CT coronary angiography in the detection of significant stenoses (defined as > or = 50% luminal diameter reduction) versus invasive quantitative coronary angiography (QCA). Thirty-five patients with stable angina pectoris underwent CT coronary angiography performed with a 64-slice scanner (gantry rotation time 330 ms, individual detector width 0.6 mm) prior to conventional coronary angiography. Patients with heart rates >70 beats/min received 100 mg metoprolol orally. One hundred millilitres of contrast agent with an iodine concentration of 400 mgl/ml were injected at a rate of 5 ml/s into the antecubital vein. The CT scan was triggered with the bolus tracking technique. The sensitivity, specificity and the positive and negative predictive values of 64-slice CT were 99%, 96%, 78% and 99%, respectively, on a per-segment basis. The values obtained on a per-patient basis were 100%, 90%, 96% and 100%, respectively. When referral to catheterisation is questionable, CT coronary angiography may identify subjects with normal angiograms and consistently decrease the number of unnecessary invasive procedures. |
| Databáze: | OpenAIRE |
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