Diet quality and risk of parkinson’s disease: The rotterdam study
| Autor: | Trudy Voortman, Anne J. Strikwerda, Lisanne J. Dommershuijsen, M. Kamran Ikram |
|---|---|
| Přispěvatelé: | Epidemiology, Neurology |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Mediterranean diet Nutrition and Disease Etiology Population Disease Diet Mediterranean Article Rotterdam Study Internal medicine Voeding en Ziekte medicine Humans TX341-641 Prospective Studies education Aged Principal Component Analysis education.field_of_study Nutrition and Dietetics Nutrition. Foods and food supply business.industry Hazard ratio Parkinson Disease Middle Aged Confidence interval Diet Nutrition Assessment Risk factors Parkinson’s disease Female Diet Healthy business Cohort study Diet quality Food Science |
| Zdroj: | Nutrients, 13(11):3970. Multidisciplinary Digital Publishing Institute (MDPI) Nutrients, 13(11) Nutrients, Vol 13, Iss 3970, p 3970 (2021) Nutrients Volume 13 Issue 11 Nutrients 13 (2021) 11 |
| ISSN: | 2072-6643 |
| Popis: | The Mediterranean diet has been associated with the risk of Parkinson’s disease (PD), but limited research has been performed on other dietary patterns. We studied the relationship between overall diet quality and PD risk in the general population. We included 9414 participants from the Rotterdam Study, a prospective population-based study in the Netherlands. Diet was defined using a Dutch diet quality score, a Mediterranean diet score and data-driven dietary patterns constructed with principal component analysis (PCA). During an average follow-up of 14.1 years, PD was diagnosed in 129 participants. We identified a ‘Prudent’, ‘Unhealthy’ and ‘Traditional Dutch’ pattern from the PCA. We found a possible association between the Mediterranean diet (Hazard ratio (HR) per standard deviation (SD) 0.89 (95% confidence interval (CI) 0.74–1.07)), the ‘Prudent’ pattern (HR per SD 0.81 (95% CI 0.61–1.08)) and the risk of PD. However, no associations with PD risk were found for the Dutch diet quality score (HR per SD 0.93 (95% CI 0.77–1.12)), the ‘Unhealthy’ pattern (HR per SD 1.05 (95% CI 0.85–1.29)) or the ‘Traditional Dutch’ pattern (HR per SD 0.90 (95% CI 0.69–1.17)). In conclusion, our results corroborate previous findings of a possible protective effect of the Mediterranean diet. Further research is warranted to study the effect of other dietary patterns on PD risk. |
| Databáze: | OpenAIRE |
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