The Optimal Application of Transrectal Ultrasound in Staging of Rectal Cancer Following Neoadjuvant Therapy: A Pragmatic Study for Accuracy Investigation
| Autor: | Yan Wang, Yujie Yuan, Jianbo Xu, Min Tan, Yufeng Ren, Jinning Ye, Weixin Xiong, Yulong He, Shirong Cai |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Colorectal cancer medicine.medical_treatment Tumor Staging urologic and male genital diseases 03 medical and health sciences 0302 clinical medicine transrectal ultrasonography medicine rectal cancer Neoadjuvant therapy outcomes medicine.diagnostic_test accuracy Proportional hazards model business.industry Significant difference Ultrasound tumor staging medicine.disease Oncology 030220 oncology & carcinogenesis Anal verge Transrectal ultrasonography 030211 gastroenterology & hepatology Radiology business Research Paper |
| Zdroj: | Journal of Cancer |
| ISSN: | 1837-9664 |
| Popis: | Background: Transrectal ultrasound (TRUS) is a cost-effective test for preoperative assessment of rectal cancer. However, whether the accuracy of TRUS staging is correlated with tumor location remains obscured. This study is designed to explore their relationship and confirm an optimal application of TRUS in rectal cancer restaging. Methods: From 2005 to 2011, rectal cancer patients with TRUS data were retrospectively reviewed. Patients were divided into five groups according to tumor-involved rectal segment (SEG) above the anal verge: SEG I 1-3cm, II 3-6cm, III 6-9cm, IV 9-12cm, and V 12-16cm. The accuracy and long-term outcomes of tumor staging were compared between ultrasonographic and pathological stages. Results: 219 patients were included, with 55 (25.1%) in SEG I, 123 (56.2%) in SEG II, 32 (14.6%) in SEG III, 4 (1.8%) in SEG IV and 5 (2.3%) in SEG V. The overall accuracy of TRUS staging was remarkably superior to clinical staging by CT (64.8% vs. 34.7%, P |
| Databáze: | OpenAIRE |
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