Higher Creatinine Concentrations in Ethyl Glucuronide-Positive Urine Specimens Collected from Subjects in a Controlled Alcohol Abstinence Program: Is Serum Creatinine a Good Marker of Renal Function in Drinkers?
| Autor: | Johannes Kutzler, Richard Mauerer, Wolfgang Schultis, Sergej Bleicher, Aldo Eliano Polettini |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Automobile Driving Urinary system Renal function Glucuronates Urine Kidney Gastroenterology Ethyl sulfate Drug/alcohol abstinence chemistry.chemical_compound Ethyl glucuronide ethyl glucuronide Internal medicine Medicine Humans Creatinine alcohol business.industry Alcohol Abstinence renal function General Medicine Middle Aged Alcoholism chemistry Female business Biomarkers |
| Zdroj: | Alcohol and alcoholism (Oxford, Oxfordshire). 54(1) |
| ISSN: | 1464-3502 |
| Popis: | Aims The aim of this study was to examine urine creatinine concentrations in drivers submitted to controlled alcohol abstinence programs. Methods Urine samples (n = 32,210) were screened for ethyl glucuronide (EtG) by immunoassay during a 2-year period. Non-negatives underwent EtG and ethyl sulfate (EtS) confirmation by coupled-column Liquid Chromatography-Tandem Mass Spectrometry. Urine samples were tested for dilution by the analysis of creatinine content with |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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