Selenium-Doped Hydroxyapatite Nanocrystals–Synthesis, Physicochemical Properties and Biological Significance
| Autor: | Barbara Kołodziejska, Joanna Kolmas, Kamil Pajor, Lukasz Pajchel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
ionic substitution
General Chemical Engineering Chemical structure Ionic bonding chemistry.chemical_element 02 engineering and technology physicochemical properties 010402 general chemistry Bone tissue 01 natural sciences Selenate Osseointegration Inorganic Chemistry chemistry.chemical_compound medicine lcsh:QD901-999 General Materials Science Hydroxyapatites selenium hydroxyapatite Biological activity 021001 nanoscience & nanotechnology Condensed Matter Physics 0104 chemical sciences medicine.anatomical_structure chemistry Chemical engineering bioceramics lcsh:Crystallography selenite 0210 nano-technology Selenium biomaterials |
| Zdroj: | Crystals, Vol 8, Iss 5, p 188 (2018) |
| ISSN: | 2073-4352 |
| Popis: | Hydroxyapatites (HAs), as materials with a similar structure to bone minerals, play a key role in biomaterials engineering. They have been applied as bone substitute materials and as coatings for metallic implants, which facilitates their osseointegration. One of the beneficial characteristics of HA, when used to create biocompatible materials with improved physicochemical or biological properties, is its capacity for ionic substitution. The aim of the study was to present the current state of knowledge about HAs containing selenate ions IV or VI. The enrichment of HAs with selenium aims to create a material with advantageous effects on bone tissue metabolism, as well as having anticancer and antibacterial activity. The work is devoted to both methods of obtaining Se-HA and an evaluation of its chemical structure and physicochemical properties. In addition, the biological activity of such materials in vitro and in vivo is discussed. |
| Databáze: | OpenAIRE |
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