COMPARISON OF THE ACTIONS OF DIAZEPAM AND LORAZEPAM
| Autor: | J.E. Hegarty, A. C. McKAY, W.A.W. Mcgowan, John W. Dundee, J.K. Lilburn |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Diazepam
Time Factors business.industry medicine.drug_class digestive oral and skin physiology Amnesia Lorazepam Middle Aged Anesthesiology and Pain Medicine Anti-Anxiety Agents Preanesthetic Medication Sedative Anesthesia mental disorders medicine Humans heterocyclic compounds Ketamine medicine.symptom business medicine.drug |
| Zdroj: | British Journal of Anaesthesia. 51:439-446 |
| ISSN: | 0007-0912 |
| Popis: | Diazepam and lorazepam differ in potency and in the time-course of their action. As a sedative, diazepam 10 mg is equivalent to lorazepam 2-2.5 mg. Diazepam is better absorbed after oral than after i.m. administrations but this does not apply to lorazepam. The clinical effect and amnesia begin more rapidly with diazepam, but last longer following lorazepam. Lorazepam is more effective than diazepam in blocking the emergence sequelae from ketamine. Lorazepam i.v. is followed by a lesser frequency of venous thrombosis. |
| Databáze: | OpenAIRE |
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