Prevalence of Trypanosoma cruzi infection in pregnant Latin American women and congenital transmission rate in a non-endemic area: the experience of the Valencian Health Programme (Spain)
| Autor: | C. Barona-Vilar, A. Fullana-Montoro, C. González-Steinbauer, C. Parada, A. Gil-Brusola, A. Perez-Tamarit, T. Fraile, D. Bravo, L. Fernandez-Silveira, M. J. Giménez-Martí, D. Navarro, R. Borrás, M. D. Gómez |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Chagas disease Pediatrics medicine.medical_specialty Latin Americans Adolescent Epidemiology Trypanosoma cruzi Antibodies Protozoan Enzyme-Linked Immunosorbent Assay Disease Polymerase Chain Reaction Valencian Serology Young Adult Pregnancy Correspondence Health care Prevalence medicine Humans Seroprevalence Chagas Disease Pregnancy Complications Infectious biology business.industry Infant Newborn DNA Protozoan Middle Aged medicine.disease biology.organism_classification Infectious Disease Transmission Vertical language.human_language Cross-Sectional Studies Infectious Diseases Spain language Female business |
| Zdroj: | Epidemiol Infect EPIDEMIOL INFECT r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe instname |
| ISSN: | 1469-4409 0950-2688 |
| DOI: | 10.1017/s0950268811002482 |
| Popis: | SUMMARYThis study describes the results of the health programme implemented in the Valencian Community (Spain) to achieve an early diagnosis of Chagas disease in pregnant Latin American women and their newborns. During 2009 and 2010, 1975 women living in the health districts of three university hospitals were enrolled via midwives or at the time of delivery. Diagnosis of disease was performed using two serological tests with different antigens. Congenital infection was diagnosed by parasitological, molecular or serological methods from blood samples obtained at birth or in subsequent controls. The overall seroprevalence of Chagas infection in pregnant women from 16 different endemic countries was 11·4%. Infection was higher in those from countries in the Gran Chaco Region (Bolivia, 34·1%; Paraguay, 7·4%; Argentina, 5·3%). Eight newborn infants from Bolivian mothers had congenital Chagas which represents a vertical transmission rate of 3·7%. In conclusion, this work supports the benefits of offering an early diagnosis to pregnant women and newborns during routine prenatal healthcare. |
| Databáze: | OpenAIRE |
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