Safety trial of Floseal® haemostatic agent in head and neck surgery
| Autor: | Z Awad, R Farrell, A Ujam, T Tatla, G Wong |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Ent Surgery Adolescent medicine.medical_treatment Wound Breakdown Blood Loss Surgical Laryngectomy Salivary Gland Diseases Hemostatics Head and neck Young Adult Hematoma medicine Humans Prospective Studies Prospective cohort study Adverse effect Aged Aged 80 and over Floseal® business.industry General Medicine Middle Aged medicine.disease Thrombosis Gelatin Sponge Absorbable Thyroid Diseases Hemostasis Surgical Surgery Clinical trial Hemostasis Anesthesia Female Safety business Head Neck |
| Zdroj: | Annals of The Royal College of Surgeons of England |
| ISSN: | 1478-7083 0035-8843 |
| Popis: | INTRODUCTION Floseal® (Baxter, Hayward, CA, US) can be of value in reducing blood loss and haematoma rates. The manufacturer’s warnings include allergic reaction, poor wound healing and intravascular thrombosis. We aimed to determine whether Floseal® is safe to use in various head and neck surgery (HNS) procedures. METHODS A prospective trial was conducted using Floseal® in 42 various consecutive head and neck surgery procedures. Adverse incidents were used as the main outcome measure, including allergic reaction, wound breakdown, wound infection and thrombosis. Secondary outcome measures included haematoma formation, hospital stay, drain times and output. RESULTS No adverse incidents were recorded in the trial period. Two patients developed haematomas and required surgical exploration where a bleeding vessel was identified and dealt with. CONCLUSIONS Floseal® is safe to be used in head and neck surgery with no adverse effects. A larger number and a control group are required to ascertain its value in reducing blood loss, haematoma formation, drain usage and hospital stay. |
| Databáze: | OpenAIRE |
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