Additional file 12 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers

Autor: Ballot, Elise, Galland, Loïck, Mananet, Hugo, Boidot, Romain, Arnould, Laurent, Desmoulins, Isabelle, Mayeur, Didier, Kaderbhai, Courèche, Ilie, Silvia, Hennequin, Audrey, Bergeron, Anthony, Derangère, Valentin, Ghiringhelli, François, Truntzer, Caroline, Ladoire, Sylvain
Rok vydání: 2022
DOI: 10.6084/m9.figshare.21602052.v1
Popis: Additional file 12: Supplemental figure 10 (S10): Overall survival and progression-free interval according to BRCA 1/2 mutated status and HRD score level in ER+/HER2- tumors (n = 606). All variables were adjusted on T and N stages. A–B. Forest plots of hazard ratio (HR) for the association of the clinical variables and immune scores with overall survival (A) and progression-free interval (B) according to BRCA 1/2 mutational status and HRD score level. Red lines: patients with BRCA mutated tumors, green lines: patients with BRCA WT HRD-high tumors, blue lines: patients with BRCA WT HRD-low tumors. Horizontal lines represent 95% CI. Each point represents estimated HR. The dashed vertical line indicates HR = 1. *: Wald-test p-value < 0.05.
Databáze: OpenAIRE