Pathobiology and genetics of adrenocortical carcinoma
| Autor: | James Pittaway, Leonardo Guasti |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry Adrenal cortex DNA Methylation medicine.disease Malignancy Models Biological Pathogenesis Endocrinology medicine.anatomical_structure Molecular genetics medicine Cancer research Adrenal Cortex Adrenocortical Carcinoma Adrenocortical carcinoma Humans Mitotane Radical surgery Stem cell Cell Self Renewal business Molecular Biology medicine.drug Signal Transduction |
| Zdroj: | Journal of molecular endocrinology. 62(2) |
| ISSN: | 1479-6813 |
| Popis: | Adrenocortical carcinoma (ACC) is a rare malignancy with an incidence worldwide of 0.7–2.0 cases/million/year. Initial staging is the most important factor in determining prognosis. If diagnosed early, complete surgical resection +/− adjuvant treatment can lead to 5-year survival of up to 80%. However, often it is diagnosed late and in advanced disease, 5-year survival is |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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