The Perme Mobility Index: A new concept to assess mobility level in patients with coronavirus (COVID-19) infection
| Autor: | Ricardo Kenji Nawa, Raquel Afonso Caserta Eid, Karina T. Timenetsky, C. S. Moreira, Ana Carolina Lazarin, Ary Serpa Neto, Thiago Domingos Corrêa, Andreia Pardini |
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| Přispěvatelé: | Intensive Care Medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Viral Diseases Pulmonology Epidemiology medicine.medical_treatment Single Center law.invention Cohort Studies 0302 clinical medicine Medical Conditions law Risk Factors Medicine and Health Sciences Medicine 030212 general & internal medicine Hospital Mortality Musculoskeletal System Virus Testing Aged 80 and over Multidisciplinary Middle Aged Intensive care unit Patient Discharge Hospitals Hospitalization Intensive Care Units Treatment Outcome Infectious Diseases Female Anatomy Brazil Cohort study Research Article medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Critical Care Science Hospital mortality 03 medical and health sciences Respiratory Disorders Diagnostic Medicine Internal medicine Humans Renal replacement therapy Mobility Limitation Pandemics Aged Retrospective Studies Mechanical ventilation business.industry SARS-CoV-2 COVID-19 Biology and Life Sciences 030208 emergency & critical care medicine Retrospective cohort study Covid 19 Respiration Artificial Health Care Health Care Facilities Medical Risk Factors Respiratory Infections business |
| Zdroj: | PLoS ONE PLoS ONE, Vol 16, Iss 4, p e0250180 (2021) PLoS ONE, 16(4 April):e0250180. Public Library of Science |
| Popis: | Introduction The Coronavirus Disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. Data on the mobility level of patients with COVID-19 in the intensive care unit (ICU) are needed. Objective To describe the mobility level of patients with COVID-19 admitted to the ICU and to address factors associated with mobility level at the time of ICU discharge. Methods Single center, retrospective cohort study. Consecutive patients admitted to the ICU with confirmed COVID-19 infection were analyzed. The mobility status was assessed by the Perme Score at admission and discharge from ICU with higher scores indicating higher mobility level. The Perme Mobility Index (PMI) was calculated [PMI = ΔPerme Score (ICU discharge–ICU admission)/ICU length of stay]. Based on the PMI, patients were divided into two groups: “Improved” (PMI > 0) and “Not improved” (PMI ≤ 0). Results A total of 136 patients were included in this analysis. The hospital mortality rate was 16.2%. The Perme Score improved significantly when comparing ICU discharge with ICU admission [20.0 (7–28) points versus 7.0 (0–16) points; P < 0.001]. A total of 88 patients (64.7%) improved their mobility level during ICU stay, and the median PMI of these patients was 1.5 (0.6–3.4). Patients in the improved group had a lower duration of mechanical ventilation [10 (5–14) days versus 15 (8–24) days; P = 0.021], lower hospital length of stay [25 (12–37) days versus 30 (11–48) days; P < 0.001], and lower ICU and hospital mortality rate. Independent predictors for mobility level were lower age, lower Charlson Comorbidity Index, and not having received renal replacement therapy. Conclusion Patients’ mobility level was low at ICU admission; however, most patients improved their mobility level during ICU stay. Risk factors associated with the mobility level were age, comorbidities, and use of renal replacement therapy. |
| Databáze: | OpenAIRE |
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