Effect of Serotonin on Ovulation Induced by Pinealectomy in Anovulatory Frontal-Deafferented Rats
| Autor: | B. Mess, G.P. Trentini, L. Tima |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Ovulation
Serotonin medicine.medical_specialty Endocrinology Diabetes and Metabolism media_common.quotation_subject medicine.medical_treatment Pinealectomy Serotonergic Pineal Gland Cellular and Molecular Neuroscience Pineal gland Endocrinology Estrus Pregnancy Internal medicine medicine Animals media_common Lh secretion Endocrine and Autonomic Systems business.industry Luteinizing Hormone Frontal Lobe Rats medicine.anatomical_structure Female business |
| Zdroj: | Neuroendocrinology. 12:149-152 |
| ISSN: | 1423-0194 0028-3835 |
| DOI: | 10.1159/000122164 |
| Popis: | Frontal-deafferented female rats with resultant persistent anovulatory syndrome were subjected to pinealectomy and to subsequent treatment with serotonin. Pinealectomy provokes ovulation in previously anovulatory rats bearing frontal deaffrentation. Daily intra-peritoneal administration of either 1 or 10 mg/ kg of serotonin for 30 days counteracted the ovulation-inducing effect of pinealectomy. It is suggested that pinealectomy enhances LH-mobilization via a central serotoninergic mechanism. |
| Databáze: | OpenAIRE |
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