Co-segregation of a gene encoding a deletion ligand for Tcrb-V3+ T cells with Mtv-3
| Autor: | P. Julian Dyson, Andrew M. Knight, Kyuhei Tomonari, Sue Fairchild |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Receptors
Antigen T-Cell alpha-beta Virus Integration Immunology Biology Ligands Minor Lymphocyte Stimulatory Antigens Mice parasitic diseases Genetics Superantigen Animals Gene Rearrangement beta-Chain T-Cell Antigen Receptor Gene T-cell receptor Mouse mammary tumor virus Chromosome Mapping Chromosome T lymphocyte Provirus Ligand (biochemistry) biology.organism_classification Blotting Southern Genes Mammary Tumor Virus Mouse Chromosome Deletion |
| Zdroj: | Immunogenetics. 34:227-230 |
| ISSN: | 1432-1211 0093-7711 |
| DOI: | 10.1007/bf00215257 |
| Popis: | A gene encoding the endogenous superantigen Mlsc, which deletes Tcrb-V3+ T cells in the NOD inbred mouse strain, was found to co-segregate with Mtv-3 on chromosome 11. This identifies a fourth gene encoding a deletion ligand for Tcrb-V3+ T cells and extends recently published observations in support of the hypothesis that a number of endogenous superantigens are the products of Mtv proviruses. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink