The effects of periparturient administration of flunixin meglumine on the health and production of dairy cattle
| Autor: | H.D.Putnam Dingwell, L. Neuder, N.C. Newby, David F. Kelton, Todd F. Duffield, Daniel M. Weary, Ken E. Leslie, Suzanne T. Millman |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Veterinary medicine Flunixin Ice calving Cattle Diseases Placebo 03 medical and health sciences Animal science Retained placenta Pregnancy Genetics Medicine Animals Lactation Metritis Dairy cattle business.industry 0402 animal and dairy science Parturition 04 agricultural and veterinary sciences Stillbirth medicine.disease 040201 dairy & animal science Clonixin 030104 developmental biology Milk FLUNIXIN MEGLUMINE Animal Science and Zoology Cattle Female Endometritis business Placenta Retained Food Science medicine.drug |
| Zdroj: | Journal of dairy science. 100(1) |
| ISSN: | 1525-3198 |
| Popis: | Research on the assessment and management of pain in cows following difficult or assisted calving is still limited, especially on the effects of analgesics intended to mitigate this pain. The purpose of this study was to assess the effects of flunixin meglumine on the health and production of Holstein cows after calving. In total, 34 flunixin-treated and 38 placebo-treated animals were enrolled in a precalving treatment trial. A total of 633 animals given flunixin and 632 animals administered a placebo were enrolled in a postcalving treatment trial. In both cases, animals were randomly assigned to treatment, and researchers were blind to treatment condition until after analysis. A total of 1,265 animal records were analyzed for milk production for the first 14d in milk and health outcomes for the first 30d in milk. Animals treated with flunixin meglumine before calving had a significantly increased risk of stillbirth. Animals treated immediately after calving had increased odds of having a retained placenta and, in turn, increased risk of a high temperature, decreased milk production, and an increased risk of developing metritis. The administration of flunixin meglumine within 24h of parturition is not recommended in dairy cattle. |
| Databáze: | OpenAIRE |
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