Overview: The Pathobiology of Head and Neck Cancer

Autor:	Barbara Burtness, Erica A. Golemis
Rok vydání:	2018
Předmět:	Oncology medicine.medical_specialty business.industry Head and neck cancer Locally advanced Context (language use) Multimodality Therapy Disease medicine.disease Internal medicine Subglottic larynx medicine Etiology Stage (cooking) business
Zdroj:	Molecular Determinants of Head and Neck Cancer ISBN: 9783319787619 Molecular Determinants of Head and Neck Cancer ISBN: 9781461488149
DOI:	10.1007/978-3-319-78762-6_1
Popis:	Squamous cell cancers arising in the head and neck, from the nasopharynx to the subglottic larynx, are frequently devastating cancers that afflict patients around the world. Early stage cancers are readily cured with surgery or radiation. In contrast, locally advanced or metastatic cancers require morbid multimodality therapy and nonetheless have high recurrence rates. As this book addresses this difficult disease, it has three main goals. First, it seeks to provide an introduction to the etiology and subclasses of squamous cell carcinomas of the head and neck (SCCHNs), in the context of how these differences affect prognosis. Second, it attempts to summarize the current state of understanding of the genetic, epigenetic, and protein expression changes associated with the various classes of SCCHN. Third, it seeks to define potential therapeutic targets for improved management of the disease in the future.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f69cae9244b667a8f11e2ebfca6007b https://doi.org/10.1007/978-3-319-78762-6_1 Zobrazit plný text záznamu