Effects of Multiple Ventilation Courses and Duration of Mechanical Ventilation on Respiratory Outcomes in Extremely Low-Birth-Weight Infants

Autor: Sara B. DeMauro, Michael S Kornhauser, Jay S. Greenspan, Erik A. Jensen, Kevin Dysart, Zubair H. Aghai
Rok vydání: 2015
Předmět:
Zdroj: JAMA pediatrics. 169(11)
ISSN: 2168-6211
Popis: IMPORTANCE: Extubation failure is common in extremely preterm infants. The current paucity of data on the adverse long-term respiratory outcomes associated with reinitiation of mechanical ventilation prevents assessment of the risks and benefits of a trial of extubation in this population. OBJECTIVE: To evaluate whether exposure to multiple courses of mechanical ventilation increases the risk of adverse respiratory outcomes before and after adjustment for the cumulative duration of mechanical ventilation. DESIGN, SETTING, AND PARTICIPANTS: We performed a retrospective cohort study of extremely low-birth-weight (ELBW; birth weight
Databáze: OpenAIRE