Identity of the Neoplastic Alkaline Phosphatase as Revealed With Monoclonal Antibodies to the Placental Form of the Enzyme
| Autor: | Harry Harris, Ivan Damjanov, Jeffrey H. Loose |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
musculoskeletal diseases
medicine.drug_class Placenta Urology Breast Neoplasms Ovary Adenocarcinoma Monoclonal antibody Immunoenzyme Techniques Mice stomatognathic system Antigen Antigens Neoplasm medicine Animals Humans Gastrointestinal tract biology Histocytochemistry business.industry musculoskeletal neural and ocular physiology Liver Neoplasms Antibodies Monoclonal General Medicine Alkaline Phosphatase musculoskeletal system Molecular biology Kidney Neoplasms medicine.anatomical_structure Placental alkaline phosphatase Polyclonal antibodies biology.protein Immunohistochemistry Alkaline phosphatase business |
| Zdroj: | Journal of Urology. 133:347-348 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/s0022-5347(17)48947-6 |
| Popis: | A panel of six monoclonal antibodies and a conventional polyclonal antibody raised against human placental alkaline phosphatase (ALP) were used to characterize the alkaline phosphatase detected by means of histochemistry on tumors of breast, ovary, lung, gastrointestinal tract, and kidney. Complete antigenic identity between the tumor ALP and the placental ALP was found only in one lung tumor. However, ten tumors reacted with the polyclonal antibody and some monoclonal antibodies, thus exhibiting partial identity with the placental ALP. |
| Databáze: | OpenAIRE |
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