Diabetes Mellitus: Is It Protective against Aortic Root Dilatation?
| Autor: | Xiaofeng Chen, Xiao-Hui Peng, Han Chen, Li-jiang Tang, Xian-fang Lin, Wei-fang Yu, Jian-an Wang, Jianjun Jiang, Xiaojie Xie |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Aortic root Aortic root dilatation Negative association Age Distribution Organ Culture Techniques Internal medicine Diabetes mellitus Prevalence medicine Humans Pharmacology (medical) cardiovascular diseases Sex Distribution Aorta Aged Aged 80 and over business.industry Middle Aged medicine.disease Abdominal aortic aneurysm Echocardiography Doppler Color Surgery Diabetes Mellitus Type 2 Echocardiography Hypertension cardiovascular system Cardiology Female Aortic diameter Cardiology and Cardiovascular Medicine business Aortic Aneurysm Abdominal |
| Zdroj: | Cardiology. 112:138-143 |
| ISSN: | 1421-9751 0008-6312 |
| DOI: | 10.1159/000142944 |
| Popis: | Objectives: There is evidence of a negative association between diabetes and both abdominal aortic aneurysm and aortic diameter. However, little information is available on the relation between diabetes and aortic root diameter. Methods: We studied 109 patients with type 2 diabetes. Two-dimensional echocardiography was used to measure the aortic root at the aortic annulus, the sinus of Valsalva, the sinotubular junction and the proximal part of the ascending aorta. Measured mean values were compared with 218 age- and sex-matched patients without diabetes. A comparison of the prevalence of aortic regurgitation between the 2 groups was also performed. Results: In patients with diabetes, the mean aortic root dimensions were significantly smaller than in nondiabetic patients (p < 0.05). The prevalence of aortic root dilatation was significantly higher in nondiabetic subjects than in patients with diabetes (9.63 vs. 2.75%; p = 0.025). In the multivariable regression model, diabetes was a significant negative determinant of aortic root size at all measured sites. The prevalence of aortic regurgitation tended to be higher in nondiabetic subjects than in diabetic participants (11 vs. 18.8%); however, the difference did not achieve statistical significance (p = 0.071). Conclusions: In patients with diabetes, the aortic root dimension is significantly smaller than in patients without diabetes. |
| Databáze: | OpenAIRE |
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