Investigation of Intermolecular Interaction in Molecular Complex of Tryptamine and Benzoic Acid by Solid-State 2D NMR
| Autor: | Taro Eguchi, Midori Echigoya, Masayuki Godo, Akira Terakita, Hirokazu Matsunaga, Kazuichi Umemoto, Takahiro Ueda |
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| Rok vydání: | 2004 |
| Předmět: |
Diffraction
Tryptamine Chemistry Stereochemistry General Chemistry General Medicine Benzoic Acid Tryptamines NMR spectra database chemistry.chemical_compound Crystallography Solid-state nuclear magnetic resonance Intermolecular interaction Drug Discovery Amine gas treating Nuclear Magnetic Resonance Biomolecular Two-dimensional nuclear magnetic resonance spectroscopy Benzoic acid |
| Zdroj: | Chemical and Pharmaceutical Bulletin. 52:546-551 |
| ISSN: | 1347-5223 0009-2363 |
| DOI: | 10.1248/cpb.52.546 |
| Popis: | Solid-state NMR spectra and powder X-ray diffraction of the two-component molecular complex composed of tryptamine and benzoic acid were observed to investigate the intermolecular interaction in the molecular complex. 1D (13)C CP/MAS NMR spectrum and powder X-ray diffraction pattern of the complex was clearly different from the convolution of each spectrum of the single component. 2D (1)H-(13)C heteronuclear-correlation (HETCOR) NMR technique indicated that the intermolecular interaction between the primary amine of tryptamine and the carboxyl group of benzoic acid must be related to the complex formation. |
| Databáze: | OpenAIRE |
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