Pelvic exenteration for primary and recurrent gynaecological malignancies
| Autor: | Diederik H.-J. van Leeuwen, Johannes H. W. de Wilt, Wim J. Kirkels, Maarten Vermaas, Cornelis Verhoef, A. Logmans, Anca C. Ansink |
|---|---|
| Přispěvatelé: | Surgery, Obstetrics & Gynecology, Urology |
| Rok vydání: | 2007 |
| Předmět: |
Adult
medicine.medical_specialty Genital Neoplasms Female medicine.medical_treatment Malignancy Disease-Free Survival Postoperative Complications medicine Humans Evisceration (ophthalmology) Aged Netherlands Retrospective Studies Pelvic exenteration business.industry Obstetrics and Gynecology Cancer Retrospective cohort study Middle Aged Pelvic cavity medicine.disease Pelvic Exenteration Surgery medicine.anatomical_structure Reproductive Medicine Recurrent Cancer Female Morbidity Neoplasm Recurrence Local Lateral wall business |
| Zdroj: | European Journal of Obstetrics, Gynecology and Reproductive Biology, 134(2), 243-248. Elsevier Ireland Ltd |
| ISSN: | 0301-2115 |
| Popis: | Objective: Analyse the outcome of pelvic exenteration for gynaecological malignancies in a tertiary referral center. Post-operative in-hospital morbidity, long-term morbidity, disease free and overall survival rates were studied. Study design: Between 1991 and 2004, 42 patients underwent an anterior, total or posterior exenteration for gynaecological malignancies. Follow-up was obtained from patient files; disease free and overall survival were calculated and prognostic factors were studied. Results: A pelvic exenteration was performed in 14 patients for primary and 28 patients for recurrent gynaecological cancers. In-hospital complications occurred in 19 patients (45%) of whom seven patients needed a reoperation (17%). Late complications occurred in 31 patients (75%); 21 reinterventions were performed (50%). Five-year disease free and overall survival was, respectively, 48 and 52%. Age, type of surgery, histology, localisation of the tumour, lateral wall involvement, completeness of resection and primary versus recurrent cancer were not identified as prognostic factors for recurrence or survival. Conclusion: Long-term survival is possible in about 50% of patients after pelvic exenteration for gynaecological cancers, but is associated with significant post-operative morbidity. |
| Databáze: | OpenAIRE |
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