Detection of the Pseudomonas Quinolone Signal (PQS) by cyclic voltammetry and amperometry using a boron doped diamond electrode

Autor:	Christina M. McSweeney, Fergal O'Gara, Gerard P. McGlacken, F. Jerry Reen, Jeremy D. Glennon, John H. T. Luong, Lin Zhou
Rok vydání:	2011
Předmět:	Analytical chemistry bacterium culture cyclic potentiometry chemistry.chemical_element Quinolones engineering.material Electrochemistry quinolone derivative Catalysis Pseudomonas amperometry Materials Chemistry Boron Electrodes biology Chemistry Metals and Alloys Quorum Sensing Diamond General Chemistry electrode Hydrogen-Ion Concentration bacterial strain biology.organism_classification Combinatorial chemistry pseudomonas quinolone signal Amperometry unclassified drug Surfaces Coatings and Films Electronic Optical and Magnetic Materials Quorum sensing protein analysis Pseudomonas aeruginosa Electrode Ceramics and Composites engineering Cyclic voltammetry
Zdroj:	Chemical Communications. 47:10347
ISSN:	1364-548X 1359-7345
DOI:	10.1039/c1cc13997e
Popis:	2-Heptyl-3-hydroxy-4-quinolone, known as the Pseudomonas Quinolone Signal, is a key regulator of bacterial cooperative behaviour known as quorum sensing. A simple electrochemical strategy was employed for its sensitive detection using a bare boron-doped diamond electrode by cyclic voltammetry and amperometry. PQS (and potentially other quinolones) was then detected in cultures of P. aeruginosa pqsL - mutant strains. © 2011 The Royal Society of Chemistry.
Databáze:	OpenAIRE
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