Differences between the real and the desired worlds in the results of clinical trials
| Autor: | El Dib, Regina [UNESP], Dib, Regina El, Jorge, Eliane Chaves [UNESP], Kamegasawa, Amélia [UNESP], Daher, Solange Ramires [UNESP], Spagnuolo, Regina Stella [UNESP], da Silva, Marise Pereira [UNESP], Braga, Gabriel Pereira [UNESP], Volpato, Enilze [UNESP], Módolo, Norma Sueli Pinheiro [UNESP], Betini, Marluci [UNESP], Do Valle, Adriana [UNESP], Corrêa, Ione [UNESP], Bazan, Rodrigo [UNESP], Almeida, Ricardo Augusto M. B. [UNESP], Weber, Silke Anna Theresa [UNESP], Molina, Silvana [UNESP], Yoo, Hugo [UNESP], Boas, Paulo Villas [UNESP], Corrente, José Eduardo [UNESP], Mathew, Joseph, Kapoor, Anil, Carvalho, Raíssa Pierri [UNESP], Vital, Roberto Bezerra [UNESP], Braz, Leandro Gobbo [UNESP], Do Nascimento Junior, Paulo [UNESP] |
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| Přispěvatelé: | Universidade Estadual Paulista (Unesp), McMaster University, McMaster Institute of Urology, Pediatric Pulmonology, PGIMER |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Research design
medicine.medical_specialty Efficacy Systematic survey Psychological intervention MEDLINE Effectiveness law.invention Randomized controlled trial law medicine Humans Clinical Trials Randomized Controlled Trials as Topic Clinical Trials as Topic lcsh:R5-920 Evidence-Based Medicine business.industry Research General Medicine Evidence-based medicine Clinical Science Clinical trial Clinical Practice Treatment Outcome Bibliometrics Research Design Physical therapy Clinical Medicine business lcsh:Medicine (General) |
| Zdroj: | Clinics, Vol 70, Iss 9, Pp 618-622 (2015) Clinics, Volume: 70, Issue: 9, Pages: 618-622, Published: SEP 2015 Clinics; v. 70 n. 9 (2015); 618-622 Clinics; Vol. 70 Núm. 9 (2015); 618-622 Clinics; Vol. 70 No. 9 (2015); 618-622 Clinics Universidade de São Paulo (USP) instacron:USP Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 1980-5322 1807-5932 |
| Popis: | Made available in DSpace on 2018-12-11T17:25:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-01-01. Added 1 bitstream(s) on 2019-10-09T18:32:09Z : No. of bitstreams: 1 S1807-59322015000900618.pdf: 243111 bytes, checksum: 6fbbe57cd02f4260c36d6a9a23cd10c0 (MD5) OBJECTIVE: We refer to the effectiveness (known as pragmatic or real world) and efficacy (known as explanatory or desired or ideal world) of interventions. However, these terms seem to be randomly chosen by investigators who design clinical trials and do not always reflect the true purpose of the study. A pragmaticexplanatory continuum indicator summary tool was thus developed with the aim of identifying the characteristics of clinical trials that distinguish between effectiveness and efficacy issues. We verified whether clinical trials used the criteria proposed by the indicator summary tool, and we categorized these clinical trials according to a new classification. METHOD: A systematic survey of randomized clinical trials was performed. We added a score ranging from 0 (more efficacious) to 10 (more effective) to each domain of the indicator summary tool and proposed the following classifications: high efficacy ( |
| Databáze: | OpenAIRE |
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