Adrenal lesion frequency: A prospective, cross-sectional CT study in a defined region, including systematic re-evaluation
| Autor: | Mikael Hellström, Lilian Hammarstedt, G. Götherström, Stefan Ander, Bo Wängberg, Andreas Muth, Lena Björneld, Helga Agusta Sigurjonsdottir, Erik G. Almqvist, Sture Carlsson, Håkan Widell |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study Radiography Adrenal Gland Neoplasm Adrenal Gland Neoplasms Lesion Epidemiology Adrenal Glands medicine Prevalence Humans Radiology Nuclear Medicine and imaging Adrenal lesion Prospective Studies Prospective cohort study Aged Aged 80 and over Observer Variation Sweden Incidental Findings Radiological and Ultrasound Technology business.industry Incidentaloma Reproducibility of Results General Medicine Middle Aged Cross-Sectional Studies Female Radiology medicine.symptom business Tomography X-Ray Computed Follow-Up Studies |
| Zdroj: | Acta radiologica (Stockholm, Sweden : 1987). 51(10) |
| ISSN: | 1600-0455 |
| Popis: | Background: Incidentally detected adrenal lesions have become a growing clinical problem. Purpose: To prospectively estimate and validate the prevalence of incidentally detected adrenal lesions (adrenal incidentaloma) in patients with or without malignant disease undergoing CT. Material and Methods: During 18 months all adult patients with incidentally discovered adrenal lesions detected at CT were prospectively reported from the radiology departments of all hospitals in Western Sweden (1.66 million inhabitants). Frequencies of adrenal lesions initially reported at CT and at a systematic re-evaluation were compared. The interobserver variation in blindly assessing adrenal lesions was also analyzed. Results: Adrenal lesions were reported and verified in 339 patients (193 females; mean age 69 years, range 30–94 years). Mean lesion size was 25.8 mm (range 8–94 mm). The mean frequency of originally reported adrenal lesions was 0.9% (range 0–2.4% between hospitals). The systematic re-evaluation of 3801 randomly selected cases showed a mean frequency of 4.5% (range 1.8–7.1% between hospitals). The re-evaluation revealed 177 cases with adrenal lesions, 30% of these were submitted by the local radiologist in accordance with the study design, 23% were described in the local radiology report but not submitted to the study center, while 47% were neither locally reported nor submitted. Conclusion: Adrenal lesions are under-reported in clinical practice. Prevalence figures for adrenal incidentalomas should therefore be interpreted with caution, especially in multi-center settings. |
| Databáze: | OpenAIRE |
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