Effects of parenteral administration of doramectin or a combination of ivermectin and clorsulon on control of gastrointestinal nematode and liver fluke infections and on growth performance in cattle
| Autor: | Andy A. DeRosa, Valerie K. Shostrom, Jeffery A. Gurie, Alvin F. Loyacano, T. L. Skogerboe, James C. Williams |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Fascioliasis Veterinary medicine Time Factors Nematoda Gastrointestinal Diseases Cattle Diseases Weight Gain Crossbreed Feces Random Allocation Animal science Ivermectin Hepatica Sulfanilamides parasitic diseases medicine Animals Doramectin Nematode Infections Parasite Egg Count Anthelmintics Gastrointestinal tract General Veterinary biology Fasciola hepatica Liver fluke biology.organism_classification Drug Combinations Nematode Cattle Seasons medicine.drug |
| Zdroj: | Journal of the American Veterinary Medical Association. 218:1465-1468 |
| ISSN: | 0003-1488 |
| DOI: | 10.2460/javma.2001.218.1465 |
| Popis: | Objective—To compare effects of an injectable doramectin preparation with those of an injectable ivermectin-clorsulon preparation on control of gastrointestinal nematodes and liver flukes and on growth performance in cattle.Design—Randomized complete block design.Animals—60 crossbred calves.Procedures—Calves (20/treatment group) were treated with doramectin or ivermectin-clorsulon or were not treated. Fecal samples were collected for nematode andFasciola hepaticaegg counts on day 0 and for up to 140 days after treatment. Cattle were weighed before treatment and at 28-day intervals until day 140.Results—From day 7 through day 49, nematode egg counts for calves treated with doramectin or with ivermectin- clorsulon were significantly lower than those for untreated control calves. As the study progressed beyond day 56, the percentages of cattle with fluke eggs in their feces increased, but differences in regard to these percentages were not detected among the 3 groups. Average daily gain for the doramectin-treated cattle (0.79 kg/d [1.74 lb/d]) was significantly greater than that for the cattle treated with ivermectin-clorsulon (0.71 kg/d [1.56 lb/d]); values for both groups were significantly greater than that for the control cattle (0.62 kg/d [1.37 lb/d]).Conclusions and Clinical Relevance—Results suggest that doramectin had a greater impact on subclinical gastrointestinal tract parasitism in calves, as demonstrated by growth performance, than did ivermectin- clorsulon. In the Gulf Coast region of the United States, spring-born nursing beef calves may have minimal grazing exposure toF hepaticaduring the peak fluke transmission period; therefore, mature fluke burdens may be negligible at the beginning of the fall season. (J Am Vet Med Assoc2001;218: 1465–1468) |
| Databáze: | OpenAIRE |
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