Mechanical Alterations of Rabbit Achilles’ Tendon After Immobilization Correlate With Bone Mineral Density But Not With Magnetic Resonance or Ultrasound Imaging
| Autor: | Nanthan Ramachandran, Yoichi Koike, Guy Trudel, Geoff Doherty, Martin Lecompte, Laurent Dinh, Hans K. Uhthoff |
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| Rok vydání: | 2007 |
| Předmět: |
musculoskeletal diseases
Physical Therapy Sports Therapy and Rehabilitation Hindlimb Achilles Tendon Immobilization Bone Density medicine Animals Ultrasonography Bone mineral Achilles tendon medicine.diagnostic_test business.industry Rehabilitation Ultrasound Biomechanics Magnetic resonance imaging Anatomy musculoskeletal system Magnetic Resonance Imaging Biomechanical Phenomena Tendon medicine.anatomical_structure Female Rabbits Calcaneus business |
| Zdroj: | Archives of Physical Medicine and Rehabilitation. 88:1720-1726 |
| ISSN: | 0003-9993 |
| DOI: | 10.1016/j.apmr.2007.07.034 |
| Popis: | Trudel G, Koike Y, Ramachandran N, Doherty G, Dinh L, Lecompte M, Uhthoff HK. Mechanical alterations of rabbit Achilles' tendon after immobilization correlate with bone mineral density but not with magnetic resonance or ultrasound imaging. Objective To assess the usefulness of magnetic resonance imaging (MRI), ultrasound (US) imaging, or bone mineral density (BMD) in predicting the mechanical properties of immobilized rabbit Achilles' tendons. Design Experimental study. Setting Basic university laboratory. Animals Twenty-eight rabbits. Interventions Twelve rabbits had 1 hindlimb casted for 4 weeks and 10 rabbits were casted for 8 weeks. Contralateral legs and 12 normal hindlimbs served as controls. Main Outcome Measures Achilles' tendon dimensions on MRI and US, T1- and T2-signal intensities on MRI, classification of abnormalities on MRI and US; BMD of the calcaneus with dual-energy x-ray absorptiometry. Biomechanic measures consisted of peak load, stiffness, and stress. Imaging variables were correlated with biomechanic alterations. Results Immobilized Achilles' tendons were weaker and showed decreased mechanical stress compared with their contralateral legs and controls (all P Conclusions This study established weakened mechanical properties of immobilized Achilles' tendons. BMD of the calcaneus, but not MRI and US, was predictive of the mechanical alterations in immobilized Achilles' tendons. BMD may be a useful biomarker to monitor disease and recovery in Achilles' tendons. |
| Databáze: | OpenAIRE |
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