Personalized administration of contrast medium with high delivery rate in low tube voltage coronary computed tomography angiography
| Autor: | Yang Faridah Abdul Aziz, Raja Rizal Azman Raja Aman, Sock Keow Tan, Fadhli Mohamed Sani, Kwan Hoong Ng, Zhonghua Sun, Chai Hong Yeong |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Body surface area
business.industry Image quality media_common.quotation_subject Radiation dose Coronary computed tomography angiography Low tube voltage 030204 cardiovascular system & hematology Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences Contrast medium 0302 clinical medicine Medicine Contrast (vision) Radiology Nuclear Medicine and imaging Original Article business Nuclear medicine media_common |
| Popis: | BACKGROUND: High delivery rate is an important factor in optimizing contrast medium administration in coronary computed tomography angiography (CCTA). A personalized contrast volume calculation algorithm incorporating high iodine delivery rate (IDR) can reduce total iodine dose (TID) and produce optimal vessel contrast enhancement (VCE) in low tube voltage CCTA. In this study, we developed and validated an algorithm for calculating the volume of contrast medium delivered at a high rate for patients undergoing retrospectively ECG-gated CCTA with low tube voltage protocol. METHODS: The algorithm for an IDR of 2.22 gI·s(–1) was developed based on the relationship between VCE and contrast volume in 141 patients; test bolus parameters and characteristics in 75 patients; and, tube voltage in a phantom study. The algorithm was retrospectively tested in 45 patients who underwent retrospectively ECG-gated CCTA with a 100 kVp protocol. Image quality, TID and radiation dose exposure were compared with those produced using the 120 kVp and routine contrast protocols. RESULTS: Age, sex, body surface area (BSA) and peak contrast enhancement (PCE) were significant predictors for VCE (P |
| Databáze: | OpenAIRE |
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