Transmission of Mycobacterium Tuberculosis from Tuberculosis Patients with HIV Infection or AIDS
| Autor: | John S. Witte, Walter W. Ihle, Samuel W. Dooley, George M. Cauthen, William J. Bigler, Kenneth G. Castro, Ida M. Onorato, Janice Burr |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis Adolescent Epidemiology Tuberculin Mycobacterium tuberculosis Acquired immunodeficiency syndrome (AIDS) HIV Seronegativity Internal medicine Prevalence medicine Humans Child Sida Aged Aged 80 and over AIDS-Related Opportunistic Infections biology Transmission (medicine) business.industry Infant Newborn Urban Health Infant Middle Aged medicine.disease biology.organism_classification Case-Control Studies Child Preschool Population Surveillance Immunology Florida Female Viral disease Contact Tracing business Follow-Up Studies |
| Zdroj: | American Journal of Epidemiology. 144:69-77 |
| ISSN: | 1476-6256 0002-9262 |
| DOI: | 10.1093/oxfordjournals.aje.a008856 |
| Popis: | Contacts exposed to tuberculosis patients with acquired immunodeficiency syndrome (AIDS) or human immunodeficiency virus (HIV) infection were compared with contacts of HIV-negative patients for evidence of Mycobacterium tuberculosis transmission, based on a review of records of tuberculin skin tests administered during routine health department follow-up investigations in Miami/Dade County, Florida, from 1985 through 1989. After an adjusted analysis designed to balance background prevalence, tuberculin positivity was 42.0% in 2,158 contacts of HIV-negative patients compared with 28.6% and 31.3% in 363 contacts of HIV-infected patients and 732 contacts of AIDS patients, respectively. Similar results were observed in a subset of 5- to 14-year-old contacts of United States-born black or white tuberculosis patients chosen to minimize the possibility of false-negative tuberculin tests in contacts due to undiagnosed HIV infection. Analysis of contacts as sets showed a more than expected number of sets with none or all contacts infected, but this did not differ by HIV/AIDS group. In this study, tuberculosis patients with AIDS or HIV infection were less infectious to their contacts and, in this community, exposed fewer contacts than HIV-negative tuberculosis patients. |
| Databáze: | OpenAIRE |
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