Antiphosphatidylethanolamine antibodies and the antiphospholipid syndrome
| Autor: | Boffa Mc, Sanmarco M |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Lupus anticoagulant
Pathology medicine.medical_specialty Abortion Habitual biology business.industry Phosphatidylethanolamines Enzyme-Linked Immunosorbent Assay Thrombosis Antiphosphatidylethanolamine antibodies medicine.disease Antiphospholipid Syndrome Rheumatology immune system diseases Antiphospholipid syndrome Immunology biology.protein medicine Antibodies Antiphospholipid Humans Anticardiolipin antibodies Antibody skin and connective tissue diseases business |
| Zdroj: | Lupus. 18(10) |
| ISSN: | 0961-2033 |
| Popis: | The antiphospholipid antibodies included as laboratory criteria of the antiphospholipid syndrome (APS) are antibodies reacting with anionic phospholipids – anticardiolipin antibodies and lupus anticoagulant – and with β2-glycoprotein I. However, antibodies reacting with phosphatidylethanolamine (aPE), a zwitterionic phospholipid, have also been described to be associated with the main features of APS. The objectives of this review are to describe the characteristics of aPE and to bring attention to recent evidence that aPE are correlated with the main clinical features of APS, notably, in the absence of the laboratory criteria of this syndrome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|