Pulmonary hypertension and respiratory function in parenchyma sparing surgical treatment of lung cancer
| Autor: | A. A. Kirshin, V M Napol'skikh |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Aorta
Lung cancer surgery medicine.medical_specialty Lung business.industry lcsh:R lcsh:Medicine General Medicine medicine.disease Pulmonary hypertension lung cancer FEV1/FVC ratio medicine.anatomical_structure pulmonary artery resection respiratory function medicine.artery Internal medicine pulmonary hypertension Pulmonary artery medicine Cardiology Respiratory function business Lung cancer |
| Zdroj: | Kazanskij Medicinskij Žurnal, Vol 99, Iss 6, Pp 876-879 (2018) |
| ISSN: | 2587-9359 0368-4814 |
| DOI: | 10.17816/kmj2018-876 |
| Popis: | Aim. To assess the effect of pulmonary hypertension on respiratory function in lung cancer surgery. Methods. 92 patients diagnosed with non-small cell lung cancer, among them 69 men (75 %) and 23 women (25 %), were operated on with different variants of angioplastic lobectomy (APL), the average age was 57.8 ± 6.7 years. 91 patients underwent pulmonectomy (PE), among them 87 men (95.6 %) and 4 women (4.4 %), the average age was 59 ± 8.8 years. Results. One year after angioplastic lobectomy FEV1 decreased by 0.69 liters (27 %), vital capacity decreased by 1.17 liters (32.9 %), FVC (the difference between the volumes of lungs at the beginning and at the end of forced expiration) reduced by 0.64 liters (20.5 %). After removal of the lung, dynamics of the decrease of similar indicators was 1.02 (42 %); 1.53 (43.8 %); 1.24 (40.3 %) liter respectively. The presence of a negative relationship between PA/A (pulmonary artery/aorta) and FEV1 was revealed. Thus, in the group of angioplastic lobectomy without initial pulmonary hypertension (PA/A less than 1) it was found that r = -0.42 (p < 0.01), with pulmonary hypertension (PA/A 1 or more) r = -0.4 (p < 0.01). In the group of pulmonectomy without initial pulmonary hypertension, the correlation index was -0.38 (p < 0.01), with initial pulmonary hypertension r = -0.33 (p < 0.01). Conclusion. The analysis of the functional parameters of pulmonary system after the surgery revealed statistically significant advantage of organ-saving treatment, as well as negative correlation between pulmonary hypertension and respiratory function. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|