Clinical characteristics and correlation between hearing outcomes after different episodes of recurrent idiopathic sudden sensorineural hearing loss
Autor: | Pei-Hsuan Wu, Yueng-Hsiang Chu, Hsin-Chien Chen, Chih-Hung Wang, Li-Hsiang Cheng, Jih-Chin Lee, Cheng-Ping Shih, Chia-Yi Lee |
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Rok vydání: | 2020 |
Předmět: |
Adult
Male Prognostic factor Pediatrics medicine.medical_specialty Hearing Loss Sensorineural Administration Oral Correlation 03 medical and health sciences 0302 clinical medicine Recurrence Vertigo otorhinolaryngologic diseases Medicine Humans 030223 otorhinolaryngology Glucocorticoids Retrospective Studies First episode Hyperbaric Oxygenation Injection Intratympanic biology business.industry Medical record Retrospective cohort study General Medicine Hearing Loss Sudden Middle Aged biology.organism_classification Treatment Outcome Otorhinolaryngology 030220 oncology & carcinogenesis Sudden sensorineural hearing loss Audiometry Pure-Tone Surgery Administration Intravenous Female business Rare disease |
Zdroj: | Auris, nasus, larynx. 48(5) |
ISSN: | 1879-1476 |
Popis: | Objectives Recurrent idiopathic sudden sensorineural hearing loss (ISSNHL) is a rare disease. In this study, we evaluated the correlations between hearing recovery after the first and recurrent episodes of ISSNHL and characterized the clinical features of different episodes of ISSNHL. Methods This retrospective study was conducted by reviewing medical records pertaining to the period 2008–2018. A total of 30 patients (16 male, 14 female) who had experienced at least two episodes of ISSNHL were included. All patients were had received steroid therapy (including systemic and IT) and/or hyperbaric oxygen therapy within 2 weeks after the onset of disease. The SDRG's criteria was used for the grading of hearing recovery. Results The median age at the first and second episode of ISSNHL was 48 and 53.5 years, respectively; a total of 30% of patients presented with vertigo in the first episode and 40% presented with vertigo in the second episode. The hearing outcomes of both episodes showed significant improvement after treatment. The rate of complete recovery after the first and second episodes was 46.67% and 33.33%, respectively. A significant positive correlation was observed between the treatment outcomes of the first and second episodes (r = 0.721, p Conclusion In ISSNHL, hearing recovery after a recurrent episode is significantly correlated with the hearing outcome after the initial episode (p = 0.042). The treatment outcome of the first episode is a prognostic factor for the outcomes of recurrent episodes. |
Databáze: | OpenAIRE |
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