Day 3 embryo transfer versus day 5 blastocyst transfers: A prospective randomized controlled trial
| Autor: | Kanat Pektaş M, Hatırnaz Ş |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Infertility medicine.medical_treatment intracytoplasmic sperm injection lcsh:Medicine lcsh:Gynecology and obstetrics Intracytoplasmic sperm injection Andrology 03 medical and health sciences 0302 clinical medicine medicine Blastocyst Clinical Investigation lcsh:RG1-991 embryo transfer Pregnancy 030219 obstetrics & reproductive medicine In vitro fertilisation business.industry Blastocyst Transfer lcsh:R Obstetrics and Gynecology medicine.disease Embryo transfer 030104 developmental biology medicine.anatomical_structure embryonic structures business Live birth in vitro fertilization |
| Zdroj: | Turkish Journal of Obstetrics and Gynecology, Vol 14, Iss 2, Pp 82-88 (2017) Turkish Journal of Obstetrics and Gynecology |
| ISSN: | 2149-9330 2149-9322 |
| Popis: | Objective: This study aimed to show whether transferring day 5 embryos resulted in higher implantation and pregnancy rates than transferring day 3 embryos in Turkish women undergoing an intracytoplasmic sperm injection (ICSI) cycle. Materials and Methods: A total of 190 women who had ICSI after retrieval of more than four oocytes on the day of fertilization check were randomly assigned to undergo embryo transfer either on day 3 or day 5. Results: Day 3 and day 5 transfers were statistically similar with respect to the age of woman (p=0.107), duration of infertility (p=0.528), cause of infertility (p=0.850), number of collected oocytes (p=0.119), number of metaphase II oocytes (p=0.178), number of fertilized oocytes (p=0.092), and number of transferred embryos (p=0.556). The number of grade 1 embryos was significantly higher in day 5 transfers than in day 3 transfers (p=0.001). Day 3 and day 5 embryo transfers had statistically similar implantation, clinical pregnancy, twinning, and live birth rates (p=0.779, p=0.771, p=0.183, and p=0.649, respectively). The live birth rates in singleton pregnancies conceived after day 3 and day 5 embryo transfers were statistically similar (p=0.594). Conclusion: The efficacy of blastocyst transfer is not inferior to that of embryo transfer on cleavage stage. Performing blastocyst transfer may have benefits because it is associated with acceptable pregnancy rates and morphologic assessment on day 3 has limited predictive value for subsequent embryonic development. |
| Databáze: | OpenAIRE |
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