Auger-Electron Spectra of Radionuclides for Therapy and Diagnostics

Autor: Regin Weinreich, Börje Larsson, Jiri Stepanek
Rok vydání: 1996
Předmět:
Zdroj: Acta Oncologica. 35:863-868
ISSN: 1651-226X
0284-186X
DOI: 10.3109/02841869609104038
Popis: The present paper documents the calculation of radiation spectra and of radial dose distribution around a point source for 24 selected radionuclides. The radionuclides were ordered into three groups: Nuclides potentially useful for therapy by emission of Auger electrons: 51Cr, 64Cu, 67Ga, 73Se, 75Se, 77Br, 80mBr, 94Tc, 99mTc, 114mIn, 115mIn, 123I, 124I, 125I, 167Tm, 193mPt, and 195mPt, nuclides potentially useful for therapy by alpha-particles with additional emission of Auger electrons: 212Bi, 211At and 255Fm, and nuclides potentially useful for electron Auger-therapy with simultaneous PET diagnosis: 73Se, 94Tc and 124I. The calculations imply strongly the development of labelled DNA-seeking compounds useful as carrier for the Auger- and Coster-Kronig electron-emitting radionuclides.
Databáze: OpenAIRE