THE PROGNOSIS OF THE DIFFERENT ESOPHAGEAL NEUROENDOCRINE CARCINOMA SUBTYPES: A POPULATION-BASED STUDY
| Autor: | Francisco TUSTUMI, Stefanie Sophie Buuck MARQUES, Esau Furini BARROS, Alexandre Cruz HENRIQUES, Jaques WAISBERG, André Roncon DIAS |
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| Rok vydání: | 2022 |
| Předmět: |
Esophageal Neoplasms
neuroendocrine carcinoma Gastroenterology neoplasias esofágicas esophageal neoplasms Kaplan-Meier Estimate Adenocarcinoma Prognosis Carcinoma Neuroendocrine Carcinoma Squamous Cell Carcinoma Large Cell Humans Tumores neuroendócrinos Neuroendocrine tumors Carcinoma Small Cell carcinoma neuroendócrino Neoplasm Staging Retrospective Studies |
| Zdroj: | Arquivos de Gastroenterologia v.59 n.1 2022 Arquivos de gastroenterologia Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia instacron:IBEPEGE Arquivos de Gastroenterologia, Volume: 59, Issue: 1, Pages: 53-57, Published: 15 APR 2022 |
| ISSN: | 1678-4219 0004-2803 |
| Popis: | Background Neuroendocrine neoplasms are extremely rare and account for 0.4% to 2% of all malignant esophageal neoplasms. The burden of the neuroendocrine histological type on the patients’ prognosis and survival is poorly debated. This study aimed to compare the survival rates of primary neuroendocrine neoplasms compared with adenocarcinoma and squamous cell carcinoma of the esophagus. Methods This is a retrospective cohort from the Surveillance, Epidemiology, and End Results Program database. Overall survival and cancer-specific survival were evaluated with Kaplan-Meier curves and logrank tests. Proportional Cox regression models were used to evaluate variables related to overall survival. Results After eligibility criteria, 66,528 patients were selected. The mean follow-up was 22.6 months (SD 35.6). Adenocarcinoma was predominant (62%), followed by squamous cell carcinoma (36%). Large cell carcinoma, small cell carcinoma, and mixed adenoneuroendocrine carcinoma each account for less than 1% each. On the long-term overall survival analysis, esophageal adenocarcinoma showed a better prognosis than all the other histologic types (P-value for logrank test |
| Databáze: | OpenAIRE |
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