Consecutive en-bloc liver (30%)-pancreas-duodenum-spleen-stomach transplant in Lewis rats
Autor: | S. Nam, Chang H. Yoo, Ruben F. Gittes, S. Bai, K. Kim, S. Lee, C.D. Pivetti, I.C. Hong, S.T. Niewiadomski, Paul L. Wolf |
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Rok vydání: | 2003 |
Předmět: |
Male
Reoperation medicine.medical_specialty Pathology Duodenum medicine.medical_treatment Pancreas transplantation Liver transplantation Organ transplantation medicine Animals Family Characteristics business.industry Stomach Spleen transplantation Liver regeneration Liver Regeneration Liver Transplantation Rats Surgery Transplantation surgical procedures operative medicine.anatomical_structure Rats Inbred Lew Models Animal Female Pancreas Transplantation business Spleen |
Zdroj: | Microsurgery. 23:440-442 |
ISSN: | 1098-2752 0738-1085 |
DOI: | 10.1002/micr.10173 |
Popis: | It is well-known that 30% of the remaining liver mass, following partial hepatectomy, regenerates to full original mass within 2 weeks in rats. In order to carry the transplanted rat liver to repeated transplantation, a technique of combining 30% of the liver with the pancreaticoduodenum and spleen transplantation is performed in this consecutive organ transplantation study. Our laboratory observed several 37-month-old transplanted rats by carrying through 2-3 generations, and histological disclosure were made. Because the partial liver transplants did not regenerate after the transplantation with other splanchnic organs, this technique is not so difficult though subsequent surgical maneuvers are needed and the liver histology proved entirely normal in every aspect when followed beyond the rat's life span of 24 months. |
Databáze: | OpenAIRE |
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