Human uterodomes (pinopods) do not display pinocytotic function
| Autor: | Christopher R. Murphy, Nalini Gayer, Margot J. Hosie, Susan M. Adams |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Uterus Biology Uterine epithelium Pinopod medicine Animals Humans Rats Wistar Pinocytosis Rehabilitation Cell Membrane Obstetrics and Gynecology Epithelial Cells Apical membrane Middle Aged Epithelium Rats Microscopy Electron medicine.anatomical_structure Reproductive Medicine Ultrastructure Microscopy Electron Scanning Female Function (biology) Electron Probe Microanalysis |
| Zdroj: | Human reproduction (Oxford, England). 17(8) |
| ISSN: | 0268-1161 |
| Popis: | BACKGROUND: The term 'pinopod' or 'pinopode' has been used indiscriminately since the 1970s to describe most apical structures on uterine epithelial cells and as such suggests a cross species structural functionality. This study looks at the apical cellular protrusions in rats and humans and compares their pinocytotic ability. METHODS: We have utilized standard tracer techniques in an attempt to determine the functionality of the uterine surface protrusions in the human based on results reported in rats. RESULTS: Pinopods in rat tissue demonstrated tracer uptake, but no tracer uptake in the apical protrusions of human uterine epithelium was evident. CONCLUSIONS: These findings indicate that the uterine surface protrusions observed in the human are not pinocytotic and therefore probably perform a function different from similar structures observed in rats and mice. This highlights the need to alter nomenclature from pinopods to uterodomes. |
| Databáze: | OpenAIRE |
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