| Autor: |
TAKUMA TSUKIOKA, NOBUHIRO IZUMI, HIROAKI KOMATSU, HIDETOSHI INOUE, RYUICHI ITO, SATOSHI SUZUKI, NORITOSHI NISHIYAMA |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Anticancer research. 42(6) |
| ISSN: |
1791-7530 |
| Popis: |
The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are useful biomarkers in non-small cell lung cancer (NSCLC). The aim of this study was to identify novel prognostic factors after pneumonectomy or sleeve lobectomy.The clinical courses of 68 patients with NSCLC who underwent pneumonectomy or sleeve lobectomy were retrospectively investigated.High NLR (p=0.002) and PLR (p=0.006), and large tumor (40 mm) (p=0.024) were indicative of poor prognosis in univariate analysis. High NLR (p=0.021) and large tumor (40 mm) (p=0.017) remained independent factors indicating poor prognosis in multivariate analysis. Eighteen patients with both high NLR and large tumor (40 mm) had significantly poorer prognoses than the remaining patients, 10 of them having recurrences within a short time after surgery.A high NLR and large tumor size indicate a poor prognosis after pneumonectomy or sleeve lobectomy. Our findings may be helpful in selecting optimal treatments for this subgroup of patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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