Frame-based and frameless stereotactic hematoma puncture and subsequent fibrinolytic therapy for the treatment of spontaneous intracerebral hemorrhage
| Autor: | Joachim M. Gilsbach, L. Mayfrank, Ruth Thiex, Veit Rohde, Armin Thron, Zeliha Zeki, Eberhard Uhl, Ina Rohde |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Blood volume Punctures Infections Stereotaxic Techniques Hematoma Recurrence Fibrinolysis medicine Humans Minimally Invasive Surgical Procedures Thrombolytic Therapy Aged Cerebral Hemorrhage Retrospective Studies Neuroradiology Intracerebral hemorrhage business.industry Glasgow Outcome Scale Retrospective cohort study Middle Aged Prognosis medicine.disease Surgery Catheter Treatment Outcome Neurology Anesthesia Female Neurology (clinical) Tomography X-Ray Computed business |
| Zdroj: | Journal of Neurology. 251:1443-1450 |
| ISSN: | 1432-1459 0340-5354 |
| DOI: | 10.1007/s00415-004-0554-5 |
| Popis: | Comparison of two minimally invasive procedures for the treatment of intracerebral hemorrhage and subsequent lysis with regard to technical implications and clinical outcome of the patients. Retrospective analysis of 126 patients with spontaneous supratentorial intracerebral hemorrhage treated by frame-based (n=53) or frameless (n=75) hematoma aspiration and subsequent fibrinolysis with recombinant tissue plasminogen activator (rt-PA). Data were analysed for the whole group as well as for the two subsets of patients with regard to hematoma reduction, procedure-related complications, and the early and long term clinical outcome of the patients. Functional outcome was rated using the Glasgow Outcome Scale (GOS) and Barthel-Index (median follow-up 178 weeks). The prognostic impact of patient related covariates on the GOS was analysed using logistic regression analysis. 49 out of 126 patients (38.9 %) died, 25 of them in the early postoperative period. Only 22/126 (17.5 %) had a favorable long term outcome (GOS >3). Age > 65 years was significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink